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A program for designing primer pairs that amplify multiple target sequences using DNA thermodynamics and one class support vector machines. Written in Python.
A podcast hosted by Kristin Sanford and Justin Jackson to explain recent scientific research and developments in a wide range of scientific phenomenon.
A resource and online book on neurology and neurosurgery. The book covers topics such as neurological symptoms, consciousness and unconsciousness, trauma, seizure disorders and dementia.
The Biorepository was designed to collect, process, and distribute large numbers of high quality research specimens quickly and efficiently. The data that is collected is primarily human DNA from whole blood along with other human specimen types. The data are collected, processed, stored and later distributed to support a large number of research studies. Biobanking of other specimen types include cells, RNA, serum, plasma and tissue. The Biorepository serves as a storage facility for tracking specimen inventory using bar code technologies. The Biorepository also conducts most operations using modern laboratory automation and robotics, an efficient way to avoid processing errors inherent in the handling of larger numbers of specimens.
A hybrid binning tool that achieves high binning efficiency by utilizing both "compositional" and "similarity" features of the query sequence during the binning process. SPHINX can analyze sequences in metagenomic data sets as rapidly as composition based approaches, but nevertheless has the accuracy and specificity of similarity based algorithms.
A graphical user interface (GUI) for rapid composition of HPLC-MS analysis workflows. Workflow construction is reduced to drag-and-drop of analysis tools and adding connections in between.
A database of controlled vocabulary to describe each trait as a distinguishable feature, characteristic, quality or phenotypic feature of a developing or mature plant (or individual). Some examples include: plant height, disease resistance, and photosensitivity.
Nonprofit alliance of national organizations and state teams dedicated to increasing organ, eye and tissue donation. Donate Life America manages and promotes the national brand for donation, Donate Life, and assists Donate Life State Teams and national partners in facilitating high-performing donor registries; developing and executing effective multi-media donor education programs; and motivating the American public to registeras organ, eye and tissue donors.
Neuroscience News provides "Neuroscience Videos" and corresponding articles.
The OSU Comprehensive Cancer Center Leukemia Tissue Bank Shared Resource (LTBSR) facilitates the successful translation of basic leukemia research to the clinical setting via an extensive repository of tissue samples and accompanying pathologic, cytogenetic and clinical data for ready correlation of clinical and biological results. The LTBSR, which is an NCI-sponsored biorepository, has more than 40,000 vials of cryopreserved viable cells and 13,000 vials of matched frozen plasma and/or serum samples from more than 4,000 patients treated for leukemia and other malignancies. Committed to furthering translational research efforts for OSUCCC - James members and the cancer research community, the LTBSR provides investigators with training and technical support as well as procurement, processing, storage, retrieval and distribution of clinical research materials. In many cases, the LTBSR serves as the central processing lab for multi-site trials in which the principal investigator is an OSUCCC - James member. The LTBSR's goals are to: * Provide a central collection, processing and a state-of-the-art repository for samples collected from leukemia patients treated on OSUCCC - James protocols, and * Provide materials to investigators involved in collaborative studies with OSU, who examine relevant cellular and molecular properties of leukemia and correlate these properties with clinical or population-based outcomes.
Software package that enables detection of sequence variation between metagenomic samples.
The purpose of the American Diabetes Association (ADA), GENNID Study (Genetics of non-insulin dependent diabetes mellitus, NIDDM) is to establish a national database and cell repository consisting of information and genetic material from families with well-documented NIDDM. The GENNID Study will provide investigators with the information and samples necessary to conduct genetic linkage studies and locate the genes for NIDDM. Non-Hispanic white, Hispanic, African-American, and Japanese-American multiplex NIDDM families, with a minimum of one affected sib-pair, are being collected by the eight Harold Rifkin Family Acquisition Centers. Detailed family and medical histories are obtained from all participants. Family members with diabetes have fasting blood samples drawn, while nondiabetic family members have an oral glucose tolerance test and, when possible, insulin sensitivity and insulin secretion measurements by frequently sampled intravenous glucose tolerance testing or euglycemic insulin clamp. Lymphoblastoid cell lines are established for all participants. DNA samples and extensive phenotypic data are available from the American Diabetes Association's GENNID study (Genetics of NIDDM). GENNID has collected detailed family histories and a broad array of data on 170 large pedigrees, all of which contain at least one affected sib pair, with a total of 650 affected individuals and approximately 1,200 total subjects. Included are approximately 65 Caucasian, 60 Hispanic, 25 African American, and 20 Japanese American pedigrees. In addition, GENNID also contains DNA and data on 1,000 additional affected sib pairs in each of three groups, African American, Caucasian, and Hispanic. DNA and phenotypic data, including race, gender and age, are available for all members of the pedigrees. The data set includes multiple metabolic factors, including carbohydrate metabolism, lipid metabolism, and body size measures, as well as lifestyle variables obtained by questionnaire (e.g., employment, exercise, etc.). The GENNID resource is ideally suited for genetic linkage and association studies as well as SNP discovery and typing. Investigators interested in obtaining the DNA samples and/or data will need to submit a proposal to the Association that addresses the genetics of type 2 diabetes.
A data sharing platform based on the ISA software suite - including an annotation tool and a database - that holds environmental omic data in standards-compliant format. It uses various approaches to provide new discovery, interoperability and integration opportunities for environmental scientists, including the development of tools, databases, standard and ontologies. The main tool for collecting environmental omics data from researchers is the EnvBase data catalogue. The NEBC Toolbox contains a range of tools developed by NEBC to support environmental researchers. The data include next generation sequencing, microarray and ABI sequencing technologies. ISAconfigurator and ISAcreator ensure that the extensive information relating to environmental sampling is consistently collected by the NERC experimentalists, according to the appropriate MIBBI checklist(s), and then reported centrally to NEBC. A local instance of the BII runs as an internal prototype database that will soon provide public and private access to NERC research projects outputs, as appropriate. In accordance with the NERC Data Policy, and when data sets are declared ready for public release, the NEBC team will use the ISAconverter to perform (combined) submissions to the appropriate public repositories (ENA, or SRA, ArrayExpress and PRIDE) to ensure long term stewardship.
A virtual organization that promotes transdisciplinary research into anthropogeny, or the study of human origins. The research interests are broad and include finding the structural and molecular differences between humans and apes, identifying and explaining external mechanisms, and defining the evolutionary origins of humans. The center hosts symposia as well as visiting professors for the anthropogeny graduate program.
Tissue bank that provides access to tissue samples and an anonymized version of the tissue bank database.Bank has large collection of tumour, DNA and other tissue samples from childhood cancer patients.
Software package for noise-robust soft clustering of gene expression time-series data (including a graphical user interface).
A portal for developing a community of librarians that teach and support the practice of evidence-based medicine (EBM). The site offers a forum for sharing teaching materials, discussing issues and asking for advice from colleagues.
WikiMD is a free wiki based medical encyclopedia and medical wiki community that any registered user can edit. This medical encyclopedia with articles, links, images and information on everything related to medicine and health, has great potential to provide patients with reliable health information as wikiMD is edited by users with close supervision by medical professionals. WikiMD is a sister project of Residentscafe.com - a place for medical students, residency applicants, residents, fellows and attending physicians. Major categories of WikiMD: *Video of the day *Did you know? *Gray's Anatomy *USMLE (United States Medical Licensing Examination) Wiki *Disease Index *Medical Resources *Health Encyclopedia Use the info at your own risk!
A research resource about the issues surrounding the quality of medical data and its usage for secondary purposes. This portal serves as a resource to understand the current state of medical data quality and the factors that affect it. The information is gathered from anecdotal and empirical examples from peer-reviewed journals, popular media and author contributions. Issues of importance include understanding and measuring medical data quality, contributing factors, best practices, and the effects of data quality on secondary uses of medical data.
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 13, 2016.<br/><br/>A dataset about transcriptional regulation in eukaryotic cells, including data such as transcription factors and their binding sites and profiles. Resource is in Chinese.