We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Algorithm for learning parsimonious regulatory networks from systems biology data sets de novo. Software that utilizes inference algorithm to model genetic regulatory networks.Inferelator 2.0 is scalable framework for reconstruction of dynamic regulatory network models.
An algorithm for the inference of gene regulatory networks from expression data.
A software that infers regulatory interactions between transcription factors and their targets using a compendium of gene expression profiles.
An antibody supplier based out of the Silicon Valley which has a focus on products used for proteomic research. The company supplies products such as ELISA based antibody arrays, DNA and protein microarray substrates and imaging system calibration and validation tools.
A leading scientific and technology research, development and implementation organization in Africa that undertakes directed research and development for socio-economic growth and improving the quality of life of South African citizens.
Core facility that provides the microscopy infrastructure necessary to support frontline research in biological and physical sciences at the Australian National University. Teaching and training is also available.
Software package that allows inferring gene regulatory networks with direct physical interactions from microarray expression data using C3NET.
Drosophila neurobiology with 3D images, enhancer traps, Golgi impregnations and protocols. This data contains a schematic view onto the brain of an adult fly is a clickable imagemap. The set of links overlaps with those of the 3D-clickable version, but is not identical.
Research center which facilitates advanced research on the clinical, genetic, neuropathological, neuroanatomical, biomedical, psychosocial, and neuropsychological aspects of Alzheimer's disease, as well as other related brain disorders. This center is supported by the National Institute on Aging and, more specifically, is a research arm of the Memory and Aging Project.
An organization and funder of polycystic kidney disease research to find treatments. The organization also raises awareness for the disease through education, advocacy and support.
Organization provides services, infrastructure and support for computation and data driven collaborative research and its application in industry. Operates with its members and partners delivering services to research throughout Queensland and increasingly via Commonwealth programs to the nation. Members are six Queensland universities – The University of Queensland, Queensland University of Technology, Griffith University, James Cook University, CQUniversity, and the University of Southern Queensland. The University of the Sunshine Coast is an associate member. Member employees provide support and development services.
Research foundation that funds research to develop new treatments for multiple myeloma, an incurable blood cancer.
Consortium establishing data standards, tools and methods for conducting research in therapeutic areas important to public health including Alzheimer's disease, Parkinson's disease, multiple sclerosis, polycystic kidney disease, and tuberculosis.CDISC and C-Path have agreed to discontinue using separate CFAST brand, but they both remain committed to this mission and continue to partner to develop and publish therapeutic area data standards.
A software tool for predicting granzyme B and caspase cleavage sites.
An online collaborative editor for academics that use citations and/or formulas. The editor focuses on the content rather than the layout, so that with the same text, it can be published in multiple ways: On a website, as a printed book, or as an ebook.
NOTE: The T1D-RAID program is not currently accepting applications. Cooperative program that makes available, on a competitive basis, NCI resources for the pre-clinical development of drugs, natural products, and biologics to facilitate translation to the clinic of novel, scientifically meritorious therapeutic interventions for type 1 diabetes and its complications. A partial listing of those services includes: high-throughput screening, studies in animal models, formulation, pharmacology and toxicology studies, and bulk substances acquisition. Requests to T1D-RAID are brief (20 pages or less), and should clearly outline the resources required to ready the proposed therapeutic agent for clinical trials. T1D-RAID should enable entry into the clinic of promising molecules that are not otherwise likely to receive an adequate and timely clinical test. T1D-RAID is designed to accomplish the tasks that are rate-limiting in bringing discoveries from the laboratory to the clinic. Once a project has been approved, NIDDKstaff interact directly with the Principal Investigator (PI). NCI contractors perform the T1D-RAID-approved tasks under the direction of NIDDKand NCI staff. The required tasks will vary from project to project. In some cases T1D-RAID will support only one or two key missing steps necessary to bring a compound to the clinic; in other cases it may be necessary to supply the entire portfolio of development requirements needed to file an IND. Examples of tasks that can be supported by T1D-RAID include, but are not limited to: * Definition or optimization of dose and schedule for in vivo activity * Development of pharmacology assays * Conduct of pharmacology studies with a pre-determined assay * Acquisition of bulk substance (GMP and non-GMP) * Scale-up production from lab-scale to clinical-trials lot scale * Development of suitable formulations * Development of analytical methods for bulk substances * Production of dosage forms * Stability assurance of dosage forms * Range-finding initial toxicology * IND-directed toxicology, with correlative pharmacology and histopathology * Planning of clinical trials * Regulatory affairs, so that FDA requirements are likely to be satisfied by participating investigators seeking to test new molecular entities in the clinic * IND filing advice The output of T1D-RAID activities will be both products and information that will be made fully available to the originating investigator for support of an IND application and clinical trials. T1D-RAID does not sponsor clinical trials.
A software package for the prediction of calpain cleavage sites.
A standard next-generation paper (NGP) digital format for reading and digitally archiving scientific research papers to offer better imaging, data sharing and an improved reading experience. The NGP format is designed to retain traditional elements (i.e. Abstract, Introduction, etc.). Papers are viewed using any web browser running on any computing platform, including mobile devices. A button menu system provides navigation between pages. The format provides a more streamlined reading experience by providing as much information to the reader inline as possible, without requiring the user to skip between pages. To accomplish this, pop-up figure and reference details provide additional information without disrupting the flow of the paper. Clicking on standard figure data reveals full-resolution images, and live web links can be optionally followed from pop-up citations or inline links for additional information. Multimedia, such as hi-definition video or audio clips, is easily embedded within the new NGP format. The reader may also customize their reading experience by selecting alternative text and background color themes. The NGP format was created using non-proprietary open-source software including HTML and Javascript, and can be packaged to run offline independent of a live Internet connection. Data are fully captured and communicated utilizing the latest technologies available. The SCORE Imaging (Petzold et al.) paper was submitted to the publisher using this format to take advantage of its superior technical capabilities (http://zfishbook.org/NGP/).
A database of resources on cancer processes such as cell death. It is a subset of a larger database on cancer proteomics that focuses on anti-cancer drugs and cancer types in addition to cancer processes. It utilizes scientific articles from PubMed, UniProt and other resources along with information such as author information, sample types and useful hyperlinks.
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30, 2022. Software package that implements 12 major meta-analysis methods for differential expression analysis.Package was removed from the CRAN repository.Formerly available versions can be obtained from the archive.Archived on 2018-01-23 as check problems were not corrected in time.